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Simbiome is a curated, online electronic resource that organizes and presents relevant resources for physics-based simulation of biomedical structures and related entities in biology and life sciences.
S2S - Sequence to Structure
Framework to display, manipulate and interconnect RNA data from the sequence to the structure
http://bioinformatics.org/S2S/
| Software: Support Tool | |
S2S (for Sequence To Structure) is a Java framework providing several graphical tools to easily display and manipulate RNA data from the sequence to the structure. The tools provided are :
S2S has been designed to construct multiple alignments against RNA molecules for which a tertiary structure is known. One starts by opening an RNA tertiary structure stored in a PDB file. S2S displays the tertiary structure with Rna3DViewer, automatically derives the corresponding RNA secondary structure with Rna2DViewer, and allows to construct multiple alignments against the RNA primary sequences with Rnalign. All these tools are interconnected. At any moment during the construction of the multiple alignment, S2S highlights the position where you are in the 2D and 3D structures. At any moment during the manipulation of the secondary structure, S2S highlights the position where you are in the multiple alignments and in the 3D structure. If you want to keep one view unchanged, each tool enables you to unlink it from the others. If no 3D structures are available, S2S can be used to open an MFold secondary structure (stored in an RnaML file) and to make multiple alignments against the RNA sequence. Finally, Rnalign can be used to make multiple alignments against RNA sequences with unknown secondary and tertiary structures. | |
| Development Stage | 4 - Development with public userbase |
| Keywords | |
| License | None - no license, public domain |
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This work is licensed under a Creative Commons Attribution 2.5 License.